Horizon Europe · GenAI4EU

ResPECT

Generative AI Assistant — A Paradigm Shift in Burden Assessment for Cancer and Mental Health Care

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About ResPECT

Turning patient narratives into insight that changes care

ResPECT is a Horizon Europe project developing an innovative Generative AI solution to improve how patient burden is identified, understood, and addressed in cancer and mental health care. By transforming patient narratives into structured and actionable insights, ResPECT aims to improve quality of life, support clinical decision-making, and strengthen healthcare system planning.

Through close collaboration with patients, healthcare professionals, researchers, technology developers, and policymakers, the project places users at the centre of innovation.

European Commission initiative

GenAI4EU Health Cluster

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ResPECT is part of five projects in the GenAI4EU Health Cluster, set up by the European Commission with the ambition to develop trustworthy and human-centred GenAI for healthcare and biomedical research. Together with GenAI4Care, ResPECT focuses on developing GenAI solutions around the needs of patients, caregivers and healthcare professionals. However, ResPECT additionally aims to translate patient experiences into insights that can support the bigger picture of health policy and system-level decision-making.

The ResPECT Virtual Assistant

From a patient's own words to population-level intelligence — one AI core, two assistants, three audiences.

01 · Input

Patient

Describes symptoms, feelings and daily life in their own words — by voice, chat or text, in their own language.

Voice & text input

02 · Core

AI Agent

A trustworthy, multilingual generative AI core that structures narratives together with patient-reported outcomes and clinical data.

Explainable

Privacy-by-design

Human oversight

03 · Assistants

Medical Assistant

Structured summaries with guideline-linked recommendations for clinicians.

Policy

Policy Assistant

A dashboard of real-time burden trends for policymakers and health systems.

Feedback loop

Tailored and medically approved feedback and assistance returns to the patient — and population-specific insight improves care for everyone.

Why breast cancer and depression

Cancer & mental health focus

Breast cancer and depression were selected because both involve complex, evolving burdens that are not fully captured by standardised questionnaires alone. Together, they allow ResPECT to test its approach across two distinct care settings and assess whether patient narratives can improve support for patients, healthcare professionals and health systems.

Breast cancer

Breast cancer was selected because patients often experience complex and changing burdens throughout treatment and survivorship, including physical symptoms, emotional distress, social challenges and financial strain. Although patient-reported outcome measures are increasingly used in cancer care, they may not fully capture these lived experiences or translate them into timely, guideline-linked clinical action.

Depression

Depression was chosen because symptoms and patient experiences are highly individual, dynamic and often difficult to express through standardised questionnaires alone. Effective care depends on understanding emotional state, context and changes over time, while digital tools must also be sensitive, trustworthy and accessible.

Across Europe

Where the consortium works

Hover a location to see the partner organisations based there.

Partner location (hover for details) Countries with ResPECT partners

Head-office locations shown. Still to confirm: Kraftvoll Technologies GmbH / CANKADO · Gemeinsam gegen Brustkrebs e.V. (TABC) (both Germany).

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22 partners, 8 countries

Universities, hospitals, technology partners and patient organisations across Europe.